Why the study?
Female sex has been repeatedly associated with AF-related stroke risk, yet trends toward lower use of oral anticoagulants in women with AF have been reported.
This review highlights the importance of considering female sex in thromboembolic risk stratification for patients with atrial fibrillation.
Suggests possible sex-based disparities in AF care; hypothesis-generating and should not yet change practice.
Stroke prevention is crucial for the management of patients with atrial fibrillation (AF), and several risk factors have been identified, which increase the risk of AF-related stroke. Among these factors, female sex has been repeatedly associated with AF-related stroke risk; nonetheless, trends toward lower use of oral anticoagulant in women with AF were also reported. In this clinical focus, we discuss about the role of female sex as a risk factor for AF-related stroke, and reflect on the clinical implications of its inclusion among the risk factors for thromboembolic risk stratification in patients with AF.
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Corica et al. (2023) studied this question.
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