Prediction of Cardiovascular Events and All-Cause Mortality With Brachial-Ankle Elasticity Index
Why the study?
Does a high brachial-ankle elasticity index (baEI) predict an increased risk of cardiovascular events and all-cause mortality?
Population
Participants in longitudinal cohort studies
Comparison
High brachial-ankle elasticity index (baEI) vs Low brachial-ankle elasticity index (baEI)
Design
Meta-analysis
Follow-up
mean 3.6 years
Authors
Discussion
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Member takes
Implication
High baEI signals nearly threefold CV risk elevation; reinforces arterial stiffness as prognostic marker while leaving therapeutic use open.
Structured PICO
Does a high brachial-ankle elasticity index (baEI) predict an increased risk of cardiovascular events and all-cause mortality?
P
Population
Participants in longitudinal cohort studies
I
Intervention
High brachial-ankle elasticity index (baEI)
C
Comparator
Low brachial-ankle elasticity index (baEI)
O
Outcome
Total cardiovascular events, cardiovascular mortality, and all-cause mortalityhard clinical
Higher brachial-ankle elasticity index (pulse wave velocity) is a significant predictor of total cardiovascular events, cardiovascular mortality, and all-cause mortality.
Limitations
- Lack of data in non-Asian populations
- Need for validation of path length estimation
- Need for determination of reference values
- Lack of prospective comparison with carotid-femoral pulse wave velocity
Cite This Study
Vlachopoulos et al. (2012) studied this question.