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April 4, 2026Therapeutic Delivery0 citations

Aloe-emodin microemulsion gel for diabetic wounds: optimizing surfactant–polymer synergy for effective wound management

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PPPankaj PopliSGSakshi GaurSDShilpa Devi

Key Points

  • The aim is to evaluate the effectiveness of aloe-emodin microemulsion gel in managing diabetic wounds.
  • Developed a microemulsion gel using surfactant and polymer combinations.
  • Tested the solubility and bioavailability of aloe-emodin in the gel.
  • Assessed the penetration and release characteristics of the gel on wound models.
  • The microemulsion gel significantly improved the solubility of aloe-emodin.
  • Enhanced the penetration of the gel into diabetic wounds was observed.
  • Controlled release of aloe-emodin promoted effective healing compared to traditional treatments.

Abstract

AMEG effectively overcomes the solubility and bioavailability limitations of Aloe-emodin, offering a promising topical therapeutic strategy for diabetic wound management through enhanced penetration, controlled release, and synergistic healing effects.

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Cite This Study

Popli et al. (2026) studied this question.

synapsesocial.com/papers/69d0ae68659487ece0fa46a8https://doi.org/10.1080/20415990.2026.2653453
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