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CAR-T therapy for relapsed/refractory large B-cell lymphoma in people living with HIV: efficacy, toxicity and treatment considerations. | Synapse
April 4, 2026
Open Access
CAR-T therapy for relapsed/refractory large B-cell lymphoma in people living with HIV: efficacy, toxicity and treatment considerations.
AH
Angela Hwang
AK
Amy A. Kirkwood
PH
Prudence Hardefeldt
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Key Points
To evaluate the efficacy and toxicity of CAR-T therapy for treating relapsed/refractory large B-cell lymphoma in individuals living with HIV.
Assessment of CAR-T therapy outcomes in HIV-positive patients
Evaluation of treatment toxicity levels
Comparative analysis of efficacy in relapsed/refractory cases
CAR-T therapy demonstrates significant patient response rates in large B-cell lymphoma
Toxicity profile reveals manageable side effects
Considerations for tailored treatment approaches in HIV-positive individuals are emphasized
Abstract
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Cite This Study
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Hwang et al. (Thu,) studied this question.
synapsesocial.com/papers/69d0ae94659487ece0fa48cc
https://doi.org/https://doi.org/10.3324/haematol.2025.300151