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April 4, 2026FoundationsOpen Access

Efficient and Structure-Preserving Numerical Methods for Time–Space Fractional Diffusion in Heterogeneous Biological Tissues

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Authors

JRJ. Rodrigues

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Overview

Numerical methods improve accuracy and efficiency in modeling transport in biological tissues, suggesting advances in computational techniques.

Key Points

  • The aim is to develop a numerical method for time-space fractional diffusion that effectively models anomalous transport in heterogeneous biological tissues.
  • Developed a fully discrete numerical method integrating heterogeneous diffusion coefficients.
  • Utilized finite element approximation of a spectral fractional elliptic operator.
  • Employed an implicit L1 discretization of the Caputo derivative.
  • Applied a sum-of-exponentials approximation of the memory kernel.
  • Established unconditional stability and error estimates.
  • Reduced memory complexity from O(N) to O(logN) without sacrificing accuracy.
  • Confirmed theoretical convergence rates through numerical experiments.
  • Demonstrated stable behavior in all tested configurations.
  • Illustrated the effect of heterogeneous coefficients on transport dynamics.

Cite This Study

J. Rodrigues (2026) studied this question.

synapsesocial.com/papers/69d0afb4659487ece0fa5b65https://doi.org/10.3390/foundations6020016
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