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April 5, 2026International Forum of Allergy & Rhinology0 citations

Oral Steroid Use and Asthma Comorbidity in Central Compartment Atopic Disease: The Predictive Role of Olfactory Dysfunction and Eosinophilia

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LHLin HsuChang Gung UniversityCWChia‐Chen WuChang Gung UniversityHWHsiang‐Sheng WangChang Gung Memorial Hospital

Key Points

  • The research aims to examine the relationship between olfactory dysfunction, eosinophilia, and asthma in patients with CCAD.
  • Analyzed the association of olfactory dysfunction and eosinophilia with asthma in CCAD patients.
  • Examined postoperative corticosteroid use and its predictors based on inflammation profiles.
  • Higher levels of tissue eosinophilia predict increased corticosteroid use after surgery.
  • Advanced disease and elevated blood eosinophils are linked to asthma comorbidity.

Abstract

CCAD is associated with greater subjective olfactory dysfunction and a distinct allergic inflammatory profile. Tissue eosinophilia independently predicts postoperative corticosteroid use, while advanced disease and elevated blood eosinophils predict comorbid asthma. These findings support risk stratification and personalized postoperative management in CCAD.

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Cite This Study

Hsu et al. (2026) studied this question.

synapsesocial.com/papers/69d1fc70a79560c99a0a218ehttps://doi.org/10.1002/alr.70147
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