Investigative findings reveal impaired clearance affects cortical excitability in epilepsy, suggesting new insights into treatment.
These findings demonstrate a spatially convergent link between glymphatic dysfunction, cortical activity with predominant inhibitory tone, and focal atrophy in the AH. Our results indicate that impaired perivascular clearance is correlated with altered cortical excitability, highlighting the potential role of the GS in maintaining neural stability in the epilepsy.
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Fu et al. (2026) studied this question.
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