What question did this study set out to answer?

To investigate the relationship between chronic venous disease and recurrent venous ulcers in a patient with multiple cardiovascular issues.

April 5, 2026Open Access

Non-Healing Venous Ulcer Associated With the Triple Threat of Deep Vein Reflux, Tricuspid Valve Regurgitation, and Pulmonary Hypertension

Key Points

To investigate the relationship between chronic venous disease and recurrent venous ulcers in a patient with multiple cardiovascular issues.
Case report of a 72-year-old man
Assessment of bilateral malleolar venous ulcers
Evaluation of underlying vascular and cardiac conditions
Patient presented with recurrent venous ulcers
Identified factors include deep vein reflux, tricuspid valve regurgitation, and pulmonary hypertension
Each condition contributes to ambulatory venous hypertension

Abstract

Chronic venous disease (CVD) of the lower extremities comprises a spectrum of venous disorders leading to ambulatory venous hypertension and inflammation due to obstruction, reflux, or both. Chronic venous disease is the leading cause of venous leg ulcers. This case report presents a 72-year-old man who presented with recurrent bilateral malleolar venous ulcers associated with 3 pathological processes, each contributing to ambulatory venous hypertension.Clinical ImpactThis case report suggests that numerous factors can contribute to ambulatory venous hypertension and by extension venous ulceration.

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