Skin booster non-animal stabilized hyaluronic acid and abobotulinumtoxinA in the management of acne scars and glabellar lines: A real-world case series of five patients

Facial aging and acne scarring commonly coexist, leading to textural irregularities and esthetic concerns in adults. Conventional resurfacing options often yield variable results, whereas skin booster non-animal stabilized hyaluronic acid (SB-NASHA) microinjections enhance hydration, elasticity, and scar appearance. When combined with energy-based devices (EBDs) or abobotulinumtoxinA (AboBoNT-A), complementary clinical improvements may be observed. Five Fitzpatrick skin type V patients (one male and four females) presented with pores, lines, atrophic scars, dullness, and pigmentary changes; two also had glabellar lines. All patients received SB-NASHA using SmartClick™ technology, with three also treated with Q-switched laser and two with AboBoNT-A. Outcomes assessed using the global aesthetic improvement scale, skin quality assessment scale, and Glabellar line severity score (GLSS) showed consistent improvement in radiance, texture, firmness, and scar appearance. Glabellar lines in Cases 4 and 5 improved from GLSS 2 to 0. All patients achieved “Very Satisfactory” ratings on physician and patient global evaluations. SB-NASHA, alone or combined with EBD or AboBoNT-A, improved skin quality and glabellar lines, supporting its role in individualized facial rejuvenation.