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April 6, 2026npj Science of FoodOpen Access

Resistant starch-enriched rice varieties improve glucose homeostasis in diabetic mice via modulation of the intestine-liver-pancreas axis

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Authors

JZJiarui ZengPLPing LiHCHao Chen

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Overview

Investigation of resistant-starch-rich rice effects on glucose control in diabetic mice, suggesting new dietary solutions.

Key Points

  • This study aims to analyze the efficacy of resistant-starch-rich rice varieties in improving glucose homeostasis in diabetic mice.
  • Utilized a high-fat diet-induced type 2 diabetic mouse model.
  • Conducted a 6-week feeding trial with two resistant-starch-rich rice varieties and a common rice cultivar.
  • Measured fasting blood glucose, blood lipids, insulin levels, and intestinal health.
  • Analyzed the impact on pancreatic pathology and liver function.
  • Resistant starch-enriched rice varieties reduced fasting blood glucose and blood lipids.
  • KTD rice variant was found to be the most effective in controlling blood glucose response.
  • Alleviated pancreatic tissue damage and improved insulin resistance metrics.
  • Enhanced gut health by repairing intestinal barriers and promoting beneficial gut flora.

Cite This Study

Zeng et al. (2026) studied this question.

synapsesocial.com/papers/69d34d5c9c07852e0af975c9https://doi.org/10.1038/s41538-026-00792-w
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