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Demonstrates a nanotherapeutic strategy that restores amyloid-β clearance in Alzheimer's disease mice, suggesting potential treatments for related conditions.
Our study not only elucidates a HDAC4-NHE6-pH regulatory axis in AD pathogenesis but also establishes a multifaceted nanotherapeutic strategy for restoring Aβ homeostasis. Our findings may provide therapeutic strategies for treating amyloid-related diseases.
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Huang et al. (2026) studied this question.
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