October 4, 2022Open Access

Overrepresentation of Enterobacteriaceae and Escherichia coli is the major gut microbiome signature in Crohn’s disease and ulcerative colitis; a comprehensive metagenomic analysis of IBDMDB datasets

BKBabak KhorsandUniversity of California, Irvine HAHamid Asadzadeh AghdaeiResearch Institute for Endocrine Sciences EMEhsan Nazemalhosseini MojaradShahid Beheshti University of Medical Sciences

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Abstract

In conclusion, compared with healthy people, the taxonomic and functional composition of intestinal bacteria in CD and UC patients was significantly shifted to Enterobacteriaceae species, mainly E. coli and Klebsiella species.

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