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July 7, 2010European Heart Journal198 citationsOpen Access

Shock in acute myocardial infarction: the Cape Horn for trials?

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HTH ThieleBABachir AllamGCGilles Châtellier

Key Points

  • This review aims to explore the causes, pathophysiology, and treatment options for cardiogenic shock complicating acute myocardial infarction.
  • Review of current therapeutic strategies including percutaneous coronary intervention, inotropes, and mechanical devices.
  • Assessment of limited evidence supporting various treatment approaches.
  • Focus on interventional techniques and advancements in pharmacological and mechanical therapies.
  • Cardiogenic shock is identified as the leading cause of death in acute myocardial infarction.
  • Current treatment methods lack robust supportive evidence.
  • Advancements in interventional techniques are necessary to improve outcomes for cardiogenic shock.

Abstract

Despite therapeutic improvements, cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, fluids, adjunctive medication, intra-aortic balloon counterpulsation, and also assist devices are widely used for treatment. However, currently, there is only limited evidence for any of the above treatments. This review will therefore outline the underlying causes, pathophysiology, and treatment of CS complicating AMI with major focus on interventional techniques and advancement of new therapeutical arsenals, both pharmacological and mechanical.

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Cite This Study

Thiele et al. (2010) studied this question.

synapsesocial.com/papers/69d48a6595972252e7dc759ehttps://doi.org/10.1093/eurheartj/ehq220
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