Why the study?
Does neoadjuvant chemotherapy followed by surgery improve outcomes in primary pulmonary leiomyosarcoma?
Does neoadjuvant chemotherapy followed by surgery improve outcomes in primary pulmonary leiomyosarcoma?
Neoadjuvant doxorubicin followed by complete surgical resection can be an effective treatment strategy for primary pulmonary leiomyosarcoma.
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May support neoadjuvant doxorubicin plus resection in pulmonary leiomyosarcoma; hypothesis-generating and leaves open need for prospective trials.
We encountered a case of primary pulmonary leiomyosarcoma that was successfully treated by surgery after neoadjuvant chemotherapy. Doxorubicin monotherapy was effective in this case. Surgery combined with neoadjuvant chemotherapy should be considered for such cases, as a long-term survival can be achieved by complete resection of primary pulmonary leiomyosarcoma.
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Tanaka et al. (2019) studied this question.
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