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January 1, 1986Medical Care5,387 citations

Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence

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DMDonald E. MoriskyLGLawrence W. GreenDLDavid M. Levine

Structured PICO

Does a high score on a four-item self-reported adherence measure predict adequate long-term blood pressure control in patients with essential hypertension?

P
Population
Patients with essential hypertension who completed a formalized 18-month educational program
I
Intervention
High score on a structured four-item self-reported adherence measure (assessed at year 2)
C
Comparator
Low score on the structured four-item self-reported adherence measure
O
Outcome
Adequate blood pressure control at 2 years (concurrent validity) and 5 years (predictive validity)surrogate

A simple four-item self-reported adherence measure demonstrates significant concurrent and predictive validity for long-term blood pressure control in hypertensive patients.

Abstract

Adherence to the medical regimen continues to rank as a major clinical problem in the management of patients with essential hypertension, as in other conditions treated with drugs and life-style modification. This article reviews the psychometric properties and tests the concurrent and predictive validity of a structured four-item self-reported adherence measure (alpha reliability = 0.61), which can be easily integrated into the medical visit. Items in the scale address barriers to medication-taking and permit the health care provider to reinforce positive adherence behaviors. Data on patient adherence to the medical regimen were collected at the end of a formalized 18-month educational program. Blood pressure measurements were recorded throughout a 3-year follow-up period. Results showed the scale to demonstrate both concurrent and predictive validity with regard to blood pressure control at 2 years and 5 years, respectively. Seventy-five percent of the patients who scored high on the four-item scale at year 2 had their blood pressure under adequate control at year 5, compared with 47% under control at year 5 for those patients scoring low (P less than 0.01).

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Cite This Study

Morisky et al. (1986) studied this question.

synapsesocial.com/papers/69d56c1b75589c71d767cbb9https://doi.org/10.1097/00005650-198601000-00007
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hypertension Continuation Adherence1979 · 26 citations
  2. 2Evaluation of Family Health Education to Build Social Support for Long-Term Control of High Blood Pressure1985 · 117 citations
  3. 3Can simple clinical measurements detect patient noncompliance?1980 · 521 citations
  4. 4Bringing the models together: An empirical approach to combining variables used to explain health actions1980 · 290 citations
  5. 5Compliance in hypertension management: What the physician can do1979 · 4 citations