Why the study?
Does advanced therapy for pulmonary arterial hypertension reduce the risk of death in adults with Eisenmenger syndrome?
Does advanced therapy for pulmonary arterial hypertension reduce the risk of death in adults with Eisenmenger syndrome?
Advanced therapy for pulmonary arterial hypertension in adults with Eisenmenger syndrome is associated with improved survival, hemodynamics, and functional class.
May support advanced PAH therapy in Eisenmenger syndrome; leaves open need for randomized confirmation.
AT for pulmonary arterial hypertension in a contemporary cohort of adults with Eisenmenger syndrome was associated with a lower risk of death. Survival benefits should be considered together with improved hemodynamics and functional class when decisions are made about AT in this population.
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Dimopoulos et al. (2009) studied this question.
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