What are the hemodynamic characteristics of long-term calcium channel blocker responders in patients with idiopathic pulmonary arterial hypertension?
Long-term responders to calcium channel blockers in IPAH are rare (<10%) but exhibit near-normal hemodynamics during acute vasodilator testing.
Long-term CCB responders represent <10% of IPAH patients evaluated in a pulmonary vascular referral center. During acute vasodilator testing, these patients showed significantly lower levels of both mean PAP and PVR, which reached near-normal values.
Sitbon et al. (2005) studied this question.