Does pleural fluid adenosine deaminase accurately diagnose tuberculous pleural effusion?
While ADA levels in pleural fluid show good diagnostic accuracy for tuberculous pleural effusion, the current evidence is limited by a high risk of bias across studies.
ADA levels in pleural fluid show good diagnostic accuracy in diagnosis of TPE; however, all included studies showed high risk of bias. It was not possible to derive any firm inference on relative clinical utility of different diagnostic thresholds.
Aggarwal et al. (Tue,) studied this question.
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