Why the study?
Does aspirin given <6 h post surgery reduce graft occlusion in patients undergoing coronary artery bypass grafting?
Does aspirin given <6 h post surgery reduce graft occlusion in patients undergoing coronary artery bypass grafting?
Administering aspirin within 6 hours after CABG optimally reduces graft occlusion without increasing bleeding risk.
Supports early aspirin post-CABG to minimize graft occlusion; confirms optimal <6 h timing from Level 1 evidence.
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether aspirin given 6 h after coronary arterial bypass grafting optimises graft patency. Altogether 201 papers were found using the reported search, of which seven presented the best evidence to answer the clinical question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these papers are tabulated. We conclude that there is good evidence that Aspirin given <6 h post surgery optimally reduces graft occlusion, without an increase in bleeding.
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G Musleh (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: