Pediatric liposarcoma has a distinct presentation compared to adult cases, with prognosis heavily dependent on the histologic subtype.
Pediatric liposarcoma has a different spectrum of presentation compared to adult cases. Myxoid liposarcoma is the more common subtype, usually occurs in extremities, and has an excellent prognosis. Pleomorphic liposarcoma occurs in axial sites, and despite multimodal therapy, outcome is poor. Further study is needed to identify the optimal therapy for pediatric liposarcoma.
Huh et al. (2011) studied this question.