Why the study?
Do two C4 EV71 vaccines induce cross-neutralizing activity in healthy Chinese infants and children?
Do two C4 EV71 vaccines induce cross-neutralizing activity in healthy Chinese infants and children?
Two C4 EV71 vaccines induce broad cross-neutralizing activity in healthy Chinese infants and children.
Supports evaluation of C4 EV71 vaccines for cross-protection in children; leaves open confirmation of clinical efficacy.
The results demonstrated broad cross-neutralizing activity induced by two C4 EV71 vaccines in healthy Chinese infants and children. However, the degree of induced cross-protective immunity, and the potential escape evolution for EV71 still need to be monitored and researched in future for these new vaccines.
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Mao et al. (2013) studied this question.