Endothelium-derived nitric oxide contributes to both the regulation of venous tone and resting venous tone in healthy humans.
NO modulates human venous tone; leaves open its role in venous disease or therapies.
Human forearm capacitance veins exhibit both stimulated and basal NO activity, which indicates that NO contributes not only to the regulation of venous tone but also to resting venous tone in healthy human subjects.
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Blackman et al. (2000) studied this question.
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