Epicardial adipose tissue in patients with cardiovascular disease exhibits a pathogenic mRNA profile, suggesting local chronic inflammation contributes to the pathogenesis of coronary artery disease.
Hypothesis-generating for epicardial fat inflammation in CAD; prospective studies needed before clinical implications.
Epicardial and omental fat exhibit a broadly comparable pathogenic mRNA profile, this may arise in part from macrophage infiltration into the epicardial fat. This study highlights that chronic inflammation occurs locally as well as systemically potentially contributing further to the pathogenesis of coronary artery disease.
No takes yet. Share an insight, caveat, or question.
Baker et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: