Left ventricular noncompaction shares a molecular etiology with other cardiomyopathic phenotypes through sarcomere protein gene defects.
We conclude that left ventricular noncompaction is within the diverse spectrum of cardiac morphologies triggered by sarcomere protein gene defects. Our findings support the hypothesis that there is a shared molecular etiology of different cardiomyopathic phenotypes.
Klaassen et al. (Wed,) studied this question.