A reduction in myocardial dendritic cells in symptomatic dilated cardiomyopathy patients correlates with worse short-term ejection fraction outcomes, potentially reflecting tissue damage and insufficient vascularization.
Myocardial DCs are reduced in heart biopsies of symptomatic DCM patients. Such a reduction correlates with an unfavourable short-term outcome in terms of EF, and could result from myocardial tissue damage, cellular death, and insufficient vascularization in chronic heart failure.
Pistulli et al. (Fri,) studied this question.