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November 21, 2007The Journal of Clinical Endocrinology & MetabolismOpen Access

Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State

Sridevi Devaraj Mohan R. Dasu Jason Rockwood William E. Winter Steven C. Griffen Ishwarlal Jialal

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Abstract

Thus, we make the novel observation that TLR2 and TLR4 expression and signaling are increased in T1DM and contribute to the proinflammatory state.

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Devaraj et al. (2007) studied this question.

synapsesocial.com/papers/69d56f8775589c71d767d973 https://doi.org/10.1210/jc.2007-2185

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