Does cryoballoon ablation or a combined approach improve single procedure success rate compared to point-by-point radiofrequency ablation in patients with paroxysmal atrial fibrillation?
Cryoballoon ablation is faster and achieves a higher single-procedure success rate than conventional radiofrequency ablation for paroxysmal atrial fibrillation, with no added benefit from a combined approach.
Pulmonary vein isolation for paroxysmal AF is faster with CRYO and results in a higher single procedure success rate than conventional point by point RFCA. The COMBINED approach was not superior to CRYO alone.
Hunter et al. (2015) studied this question.