Why the study?
Is heart rate variability associated with sensorimotor polyneuropathy in patients with Type 1 diabetes?
Is heart rate variability associated with sensorimotor polyneuropathy in patients with Type 1 diabetes?
Heart rate variability may serve as a biomarker for clinical sensorimotor polyneuropathy in Type 1 diabetes, though its prognostic value requires longitudinal validation.
HRV may indicate DSP severity in T1D; leaves open prognostic value and clinical utility pending longitudinal validation.
HRV may be a biomarker for clinical DSP and is associated cross-sectionally with both early and late measures of neuropathy. The low HRV observed in some control subjects without DSP and in most case subjects with severe DSP may signify that HRV has different prognostic implications in these groups, requiring further longitudinal study.
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Orlov et al. (2012) studied this question.
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