January 1, 2018Open Access

Carotid Plaque Stiffness Measured with Supersonic Shear Imaging and Its Correlation with Serum Homocysteine Level in Ischemic Stroke Patients

Structured PICO

Does carotid plaque stiffness measured by supersonic shear imaging correlate with serum homocysteine levels and symptomatic ischemic stroke in ischemic stroke patients?

Population

Ischemic stroke patients with carotid plaques

Intervention

Supersonic shear imaging (SSI) to measure carotid plaque stiffness (shear wave velocities, SWVs)

Outcome

Correlation of plaque stiffness (SWVs) with serum homocysteine level and association with symptomatic ischemic strokesurrogate

Supersonic shear imaging can quantitatively evaluate carotid plaque stiffness, which correlates with serum homocysteine levels and symptomatic ischemic stroke, potentially aiding in vulnerable plaque assessment.

Abstract

Supersonic shear imaging could be used to quantitatively evaluate stiffness of both echolucent and echogenic carotid plaques. More importantly, SWVs of plaques were not only correlated to serum homocysteine level, but also associated with symptomatic ischemic stroke, suggesting that SSI might be useful for understanding more about VP.

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Discussion

Journals

Korean Journal of Radiology

Institutions

Air Force Medical University

First Affiliated Hospital of Xi'an Jiaotong University

References and Citations

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