Why the study?
Are excursions of mean arterial blood pressure below the cerebral autoregulation threshold associated with acute kidney injury in patients undergoing cardiac surgery?
Population
Patients undergoing cardiac surgery
Comparison
Excursions of mean arterial blood pressure below… vs Absolute mean arterial blood pressure
Design
Cohort
Authors
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May support autoregulation-guided MAP targets in cardiac surgery; hypothesis-generating and requires RCTs before practice change.
Are excursions of mean arterial blood pressure below the cerebral autoregulation threshold associated with acute kidney injury in patients undergoing cardiac surgery?
Monitoring cerebral oximetry index to avoid blood pressure excursions below the autoregulation threshold may help prevent acute kidney injury during cardiopulmonary bypass.
Ono et al. (2012) studied this question.
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