Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels

Structured PICO

Does the biomarker profile of stress hormones, BNP, and troponin differentiate apical ballooning syndrome from STEMI?

Population

Patients with apical ballooning syndrome (Takotsubo cardiomyopathy)

Intervention

Measurement of stress hormones (catecholamine, cortisol) and circulating biomarkers (BNP, troponin)

Comparator

Patients with ST-elevation myocardial infarction (STEMI)

Outcome

Levels of stress hormones (catecholamine, cortisol) and circulating biomarkers (BNP, troponin)surrogate

Routine measurement of stress hormones is not diagnostically useful for Takotsubo cardiomyopathy, but the condition is characterized by higher BNP and lower troponin compared to STEMI.

Abstract

Catecholamine and cortisol levels were not elevated in our cohort of ABS, suggesting that routine measurement of these stress hormones is unlikely to be of diagnostic value in practice. In contrast to STEMI, ABS is characterised by a greater elevation in BNP and less myonecrosis.

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Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels

Structured PICO

Abstract

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