May 24, 2009Heart
Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels
Why the study?
Does the biomarker profile of stress hormones, BNP, and troponin differentiate apical ballooning syndrome from STEMI?
Population
Patients with apical ballooning syndrome (Takotsubo cardiomyopathy)
Comparison
Measurement of stress hormones and circulating… vs Patients with ST-elevation myocardial infarction
Design
Cohort
Authors
Discussion
Loading...
Member takes
Implication
Stress hormone testing lacks diagnostic utility in suspected Takotsubo; supports BNP/troponin distinction from STEMI but requires prospective validation.
Structured PICO
Does the biomarker profile of stress hormones, BNP, and troponin differentiate apical ballooning syndrome from STEMI?
P
Population
Patients with apical ballooning syndrome (Takotsubo cardiomyopathy)
I
Intervention
Measurement of stress hormones (catecholamine, cortisol) and circulating biomarkers (BNP, troponin)
C
Comparator
Patients with ST-elevation myocardial infarction (STEMI)
O
Outcome
Levels of stress hormones (catecholamine, cortisol) and circulating biomarkers (BNP, troponin)surrogate
Routine measurement of stress hormones is not diagnostically useful for Takotsubo cardiomyopathy, but the condition is characterized by higher BNP and lower troponin compared to STEMI.
Cite This Study
Madhavan et al. (2009) studied this question.