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September 30, 2002Circulation1,549 citationsOpen Access

Urinary Albumin Excretion Predicts Cardiovascular and Noncardiovascular Mortality in General Population

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HHHans L. HillegeHeart Failure / CardiomyopathyVFV. FidlerCentraal Bureau voor de StatistiekGDGilles F.H. DiercksUniversity Medical Center Groningen

Key Points

  • The aim is to investigate how urinary albumin excretion predicts all-cause mortality and its specific impact on cardiovascular mortality.
  • Analyzed data on urinary albumin excretion from a general population cohort.

Structured PICO

Does urinary albumin excretion predict cardiovascular and all-cause mortality in the general population?

P
Population
General population
I
Intervention
Urinary albumin excretion levels
O
Outcome
All-cause mortality, cardiovascular mortality, and noncardiovascular mortalityhard clinical

Urinary albumin excretion is an independent predictor of cardiovascular and all-cause mortality in the general population, even at levels within the currently accepted normal range.

Abstract

Urinary albumin excretion is a predictor of all-cause mortality in the general population. The excess risk was more attributable to death from CV causes, independent of the effects of other CV risk factors, and the relationship was already apparent at levels of albuminuria currently considered to be normal.

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Cite This Study

Hillege et al. (2002) studied this question.

synapsesocial.com/papers/69d5716f75589c71d767e1d2https://doi.org/10.1161/01.cir.0000031732.78052.81
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Association of Microalbuminuria and Mortality in Non—Insulin-Dependent Diabetes Mellitus1997 · 576 citations
  2. 2Lack of correlation between microalbuminuria and endothelial function in essential hypertensive patients1995 · 36 citations
  3. 3Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity2001 · 631 citations
  4. 4Urinary Albumin Excretion1999 · 438 citations
  5. 5Endothelial haemostatic factors are associated with progression of urinary albumin excretion in clinically healthy subjects: a 4-year prospective study1999 · 62 citations