Why the study?
Does invasive assessment of aortic gradient provide better prognostic value for mortality compared to echocardiography in patients undergoing TAVI?
Does invasive assessment of aortic gradient provide better prognostic value for mortality compared to echocardiography in patients undergoing TAVI?
Invasively measured, but not echocardiography-derived, transvalvular mean gradients are prognostic for mortality up to 2 years in patients undergoing TAVI.
Invasive gradients may aid TAVI mortality risk stratification; hypothesis-generating and should not yet change echo-based practice.
Only invasively measured but not echocardiography-derived transvalvular mean gradients correlate with 30-day, 1-year and 2-year mortality. Aortic gradient measurements are higher by echocardiography than by invasive assessment and more so for BEV than SEV. Smaller valve size, higher ejection fraction and higher stroke volume increase this discordance between echocardiography and invasive assessment.
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Dorpel et al. (2025) studied this question.
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