Why the study?
Is the E/e' ratio associated with fluid overload and the risk of developing diastolic dysfunction in patients with predialysis chronic kidney disease?
Is the E/e' ratio associated with fluid overload and the risk of developing diastolic dysfunction in patients with predialysis chronic kidney disease?
Regular monitoring of fluid status using BIS, NT-proBNP, and E/e' ratio may help identify predialysis CKD patients at risk for diastolic dysfunction.
May support fluid monitoring in predialysis CKD; hypothesis-generating and requires prospective validation before practice change.
Regular monitoring of fluid status by BIS and NT-proBNP can be used to find patient with risk of developing diastolic dysfunction. Treatments to correct fluid overload may reduce the risk of developing diastolic dysfunction and improve cardiovascular outcome in patients with CKD.
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Kim et al. (2017) studied this question.
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