Do polypharmacy-related interventions reduce important clinical and health care use outcomes?
Current evidence does not strongly support that polypharmacy-related interventions reduce clinical and healthcare use outcomes, highlighting a need for further research.
This updated systematic overview noted little evidence of an association between polypharmacy-related interventions and reduced important clinical and health care use outcomes. More evidence is needed regarding which interventions are most useful and which populations would benefit most.
Keller et al. (2024) studied this question.