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February 1, 2019Circulation347 citationsOpen Access

Intracardiac Delineation of Septal Conduction in Left Bundle-Branch Block Patterns

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GUGaurav A. UpadhyayTCTharian S. CherianDSDalise Y. Shatz

Structured PICO

Does intracardiac delineation of septal conduction improve the characterization of conduction block compared to surface ECG in patients with LBBB pattern?

P
Population
Patients with surface left bundle-branch block (LBBB) pattern
I
Intervention
Intracardiac delineation of septal conduction and His bundle pacing
O
Outcome
Septal conduction patterns and presence of complete conduction block (CCB)surrogate

Intracardiac mapping reveals that surface ECG criteria for LBBB incompletely predict true complete conduction block, suggesting intracardiac data may refine patient selection for cardiac resynchronization therapy.

Abstract

Heterogeneous septal conduction was observed in patients with surface LBBB pattern, ranging from no discrete block to CCB. When block was present, we observed pathology localized within the left-sided His fibers (left intrahisian block), which was most amenable to corrective His bundle pacing by recruitment of latent Purkinje fibers. ECG criteria for LBBB incompletely predicted CCB, and intracardiac data might be useful in refining patient selection for resynchronization therapy.

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Cite This Study

Upadhyay et al. (2019) studied this question.

synapsesocial.com/papers/69d575356e4506aa303c143fhttps://doi.org/10.1161/circulationaha.118.038648
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1AHA/ACCF/HRS Recommendations for the Standardization and Interpretation of the Electrocardiogram2009 · 773 citations
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  4. 4Distinctive Left Ventricular Activations Associated With ECG Pattern in Heart Failure Patients2017 · 51 citations
  5. 5Permanent His-bundle pacing: seeking physiological ventricular pacing2010 · 158 citations