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May 5, 2008Circulation2,169 citationsOpen Access

Results of the Predictors of Response to CRT (PROSPECT) Trial

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ECEugene ChungALAngel R. LeónLTLuigi Tavazzi

Structured PICO

Do echocardiographic measures of dyssynchrony improve patient selection for CRT beyond current guidelines?

P
Population
Patients evaluated for cardiac resynchronization therapy (CRT)
I
Intervention
Echocardiographic measures of dyssynchrony
O
Outcome
Response to CRT

No single echocardiographic measure of dyssynchrony is currently recommended to improve patient selection for CRT beyond standard guidelines due to high variability.

Limitations

  • Variability arising from technical and interpretative factors

Abstract

Given the modest sensitivity and specificity in this multicenter setting despite training and central analysis, no single echocardiographic measure of dyssynchrony may be recommended to improve patient selection for CRT beyond current guidelines. Efforts aimed at reducing variability arising from technical and interpretative factors may improve the predictive power of these echocardiographic parameters in a broad clinical setting.

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Cite This Study

Chung et al. (2008) studied this question.

synapsesocial.com/papers/69d575356e4506aa303c1452https://doi.org/10.1161/circulationaha.107.743120
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