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April 14, 2004JAMA1,243 citations

A Multicenter Risk Index for Atrial Fibrillation After Cardiac Surgery

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JMJoseph P. Mathew

Structured PICO

Does treatment with beta-blockers, ACE inhibitors, and/or nonsteroidal anti-inflammatory drugs prevent atrial fibrillation after CABG surgery?

P
Population
Patients undergoing CABG surgery (large multicenter international cohort)
I
Intervention
Beta-blockers, ACE inhibitors, and/or nonsteroidal anti-inflammatory drugs
O
Outcome
Occurrence of atrial fibrillation after CABG surgeryhard clinical

A multicenter risk model suggests that beta-blockers, ACE inhibitors, and NSAIDs may protect against atrial fibrillation following CABG surgery.

Abstract

We have developed and validated models predicting the occurrence of atrial fibrillation after CABG surgery based on an analysis of a large multicenter international cohort. Our findings suggest that treatment with beta-blockers, ACE inhibitors, and/or nonsteroidal anti-inflammatory drugs may offer protection. Atrial fibrillation after CABG surgery is associated with important complications.

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Joseph P. Mathew (2004) studied this question.

synapsesocial.com/papers/69d575f7c928a9acfd89a2fbhttps://doi.org/10.1001/jama.291.14.1720
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