Why the study?
Does left ventricular 2D speckle tracking echocardiography (LV GLS) discriminate GPFN individuals from normal controls in genetic dilated cardiomyopathies?
Does left ventricular 2D speckle tracking echocardiography (LV GLS) discriminate GPFN individuals from normal controls in genetic dilated cardiomyopathies?
Decreased LV GLS can detect early systolic dysfunction in genotype-positive individuals with genetic dilated cardiomyopathy, potentially allowing for earlier therapy.
May aid early GPFN detection; hypothesis-generating and requires prospective validation before practice change.
Decreased LV GLS discriminates GPFN individuals from normal controls, which may permit early institution of therapy for genetic DCM.
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Bijl et al. (2018) studied this question.
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