Retrospective cohort study reveals reduced amputation risk in critical limb ischemia patients using atherectomy with angioplasty, suggesting limited clinical benefit.
Retrospective cohort study of collected data using TriNetX Data Network Key Findings: Atherectomy with angioplasty was associated with reduced risk of minor amputations compared to angioplasty alone at 3 months to 5 years.(OR 0.74; 95% CI, 0.57-0.96).Major amputations were lower in the atherectomy group at 5 years (14.6% vs. 18.4%;OR 0.75; 95% CI, 0.57-0.99)Take Home Message: There may be limited clinical benefit to using atherectomy for first-time revascularization in patients with critical limb ischemia and isolated tibial disease. Table of Contents Summary:Using a retrospective cohort study of 1,498 CLTI patients with isolated tibial disease, Atherectomy with Angioplasty was associated with reduced risk of minor amputations compared to Angioplasty alone at 3 months and 5 years.There might be limited clinical benefit to using atherectomy for first-time revascularization in these patients.
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Ebirim et al. (2026) studied this question.
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