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April 8, 20260 citationsOpen Access

Comparative Clinical Evaluation of Virechana Karma and Jalkumbhi Bhasma in Hypothyroidism

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PKPanwar G.*1, Sharma K.2, Srivastava A. K.

Key Points

  • This research aims to compare the effectiveness of Virechana Karma and Jalkumbhi Bhasma in treating hypothyroidism.
  • Conducted with 40 patients diagnosed with hypothyroidism, following standard inclusion and exclusion criteria.
  • Patients were randomly allocated into two groups: Group-A received Virechana Karma, and Group-B received Jalkumbhi Bhasma.
  • The treatment lasted for 2 months, followed by a one-month follow-up.
  • Both treatments were effective in improving thyroid function, but Group-A (Virechana Karma) showed better overall results than Group-B (Jalkumbhi Bhasma).
  • Further studies with larger sample sizes and longer durations are recommended for better validation of the results.

Abstract

With the increased shift toward economic growth and the rising influence of Western lifestyles over the past few decades, the prevalence of lifestyle disorders has escalated to concerning levels among the Indian population. Hypothyroidism is a common endocrine disorder marked by insufficient thyroid hormone production, leading to slowed metabolism. It mainly affects women and presents with fatigue, weight gain, cold intolerance, dry skin, constipation, and depression. All metabolic activities are governed by Agni (Jatharagni, Dhatwagni, Bhutagni). Though hypothyroidism is not directly described in Ayurveda, its features correlate with Dhatwagnimandhya, where hypofunction of Jatharagni leading to impaired Dhatwagni forms the basis of disease development. Conventional management of hypothyroidism relies mainly on synthetic hormone replacement such as levothyroxine, often overlooking the underlying causes and the long-term effects of lifelong therapy. Ayurvedic interventions aim to naturally improve thyroid function, reduce dependence on synthetic drugs, and promote overall well-being, thereby offering a safer, effective, and sustainable treatment approach. The study, entitled “Comparative Clinical Evaluation of Virechana Karma and Jalkumbhi Bhasma in Hypothyroidism”, was conducted in 40 patients. They were selected on the basis of standard inclusion and exclusion criteria and randomly allocated to two different treatment groups: Group-A (Virechana Karma) and Group B (Jalkumbhi Bhasma). The total duration of treatment was 2 months, and follow-up was done 1 month after completion of treatment. Both interventions were effective, but in the overall improvement of the patients, “Group-A” had better results than “Group-B”. For better scientific validation, further research studies and clinical trials should be conducted with a larger sample size and a longer treatment duration.

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Cite This Study

Panwar G.*1, Sharma K.2, Srivastava A. K. (2026) studied this question.

synapsesocial.com/papers/69d5f05d74eaea4b11a79ba9https://doi.org/10.5281/zenodo.19436953
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A CASE STUDY ON THE EFFICACY OF VAMANA KARMA IN HYPOTHYROIDISM2024
  2. 2Effective Ayurvedic drugs after Virechana Karma in the management of Hypothyroidism: A Case Report2024 · 1 citations
  3. 3COMPARATIVE CLINICAL EVALUATION OF NIRAGNI SWEDANA, NASYA, AND VISHWADI KASHAYAM VERSUS THYROXINE SODIUM IN THE MANAGEMENT OF HYPOTHYROIDISM2026
  4. 4An Exploratory Study on the Efficacy of Ayurveda Interventions in Sub-Clinical Hypothyroidism: A Case Study2025
  5. 5Exploring the Role of Herbo-mineral Combinations for the Management of Hypothyroidism2024