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April 8, 2026Epilepsia2 citationsOpen Access

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

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BLBing‐Hua LinTaipei Medical University HospitalHHHetao HuangGuangzhou University of Chinese MedicineHLHui‐An LinTaipei Medical University Hospital

Key Points

  • The study aims to examine the association between SGLT2 inhibitors and the risk of late onset epilepsy in older adults.
  • Cohort study design conducted in a real-world setting
  • Analysis of patients using SGLT2 inhibitors
  • Follow-up to assess incidence of late onset epilepsy
  • SGLT2 inhibitor use correlated with a reduced risk of late onset epilepsy
  • Implications support etiology-specific therapeutic strategies.

Abstract

SGLT2i use was associated with reduced risk of LOE among selected patients, supporting its role in an etiology-specific therapeutic approach for older adults at risk of epilepsy.

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Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/69d5f0d774eaea4b11a7a4c7https://doi.org/10.1002/epi.70239
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