Why the study?
Does preventive PCI in noninfarct coronary arteries with major stenoses reduce adverse cardiovascular events in patients with STEMI and multivessel coronary artery disease undergoing infarct-artery PCI?
Does preventive PCI in noninfarct coronary arteries with major stenoses reduce adverse cardiovascular events in patients with STEMI and multivessel coronary artery disease undergoing infarct-artery PCI?
In STEMI patients with multivessel disease, performing preventive PCI on non-infarct arteries with major stenoses significantly reduces adverse cardiovascular events compared to culprit-lesion-only PCI.
Supports complete revascularization as standard in STEMI with multivessel disease; extends randomized evidence beyond infarct-artery PCI.
In patients with STEMI and multivessel coronary artery disease undergoing infarct-artery PCI, preventive PCI in noninfarct coronary arteries with major stenoses significantly reduced the risk of adverse cardiovascular events, as compared with PCI limited to the infarct artery. (Funded by Barts and the London Charity; PRAMI Current Controlled Trials number, ISRCTN73028481.).
No takes yet. Share an insight, caveat, or question.
Wald et al. (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: