Why the study?
Does chronic maternal hyperoxygenation improve aortic and mitral valve annular dimensions in fetuses with left heart hypoplasia?
Does chronic maternal hyperoxygenation improve aortic and mitral valve annular dimensions in fetuses with left heart hypoplasia?
In fetuses with left heart hypoplasia, chronic maternal hyperoxygenation is safe and feasible but produces only small effects on aortic and mitral valve annular growth.
No support for routine use in fetal left heart hypoplasia; leaves open whether refined protocols merit larger trials.
CMH is both safe and feasible for continued research. In this pilot study, the effect estimates of annular growth, using the studied method of delivery and dose of oxygen, were small.
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Lara et al. (2015) studied this question.
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