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January 20, 2023Journal of Clinical Oncology81 citationsOpen Access

Dexrazoxane and Long-Term Heart Function in Survivors of Childhood Cancer

ECEric J. ChowSASanjeev AggarwalDDDavid R. Doody

Structured PICO

Does dexrazoxane provide a long-term cardioprotective effect in young adult-aged survivors of childhood cancer exposed to anthracyclines?

P
Population
Young adult-aged survivors of childhood cancer with initial anthracycline exposure
I
Intervention
Dexrazoxane
O
Outcome
Long-term heart function (cardioprotective effect)

Dexrazoxane is associated with long-term cardioprotection in childhood cancer survivors nearly 20 years after anthracycline exposure.

Abstract

Among young adult-aged survivors of childhood cancer, dexrazoxane was associated with a cardioprotective effect nearly 20 years after initial anthracycline exposure.

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Cite This Study

Chow et al. (2023) studied this question.

synapsesocial.com/papers/69d6af37fca0359822aa8042https://doi.org/10.1200/jco.22.02423
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