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July 19, 2010Journal of Computational ChemistryOpen Access

NUPACK: Analysis and design of nucleic acid systems

Joseph N. Zadeh Conrad Steenberg Justin S. Bois Brian R. Wolfe Marshall B. Pierce Asif R. Khan Robert M. Dirks Niles A. Pierce

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Abstract

sequence design for complexes of nucleic acid strands intended to adopt a target secondary structure at equilibrium.Utilities: evaluation, display, and annotation of equilibrium properties of a complex of nucleic acid strands. NUPACK algorithms are formulated in terms of nucleic acid secondary structure. In most cases, pseudoknots are excluded from the structural ensemble.

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Zadeh et al. (2010) studied this question.

synapsesocial.com/papers/69d6b590733a2b54c8aa81c2 https://doi.org/10.1002/jcc.21596

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