Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

Lydia Durant; Régis Stentz; Alistair Noble; Johanne Brooks; Nadezhda Gicheva; Durga Reddi; Matthew O’Connor; Lesley Hoyles; Anne L. McCartney; Ripple Man; Edward T. Pring; Stella Dilke; Philip Hendy; Jonathan Segal; Dennis N.F. Lim; Ravi Misra; Ailsa Hart; Naila Arebi; Simon R. Carding; Stella C. Knight

doi:10.1186/s40168-020-00868-z

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Abstract

Overall, our findings suggest a key role for OMVs generated by the commensal gut bacterium Bt in directing a balanced immune response to constituents of the microbiota locally and systemically during health which is altered in IBD patients. Video Abstract.

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Durant et al. (2020) studied this question.

synapsesocial.com/papers/69d6bce78dca315383ed8b3a https://doi.org/10.1186/s40168-020-00868-z

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Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

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Abstract

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Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

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Abstract

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Cite This Study

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