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May 1, 2016Transactions of the Royal Society of Tropical Medicine and HygieneOpen Access

Policy to practice: impact of GeneXpert MTB/RIF implementation on the TB spectrum of care in Lilongwe, Malawi

Kashmira S. Chawla Cecilia Kanyama Abineli Mbewe Mitch Matoga Irving Hoffman Jonathan Ngoma Mina C. Hosseinipour

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Abstract

GeneXpert contributed minimally to overall TB diagnosis and the cascade of care due to implementation challenges of sputum collection, empiric treatment, and weak linkage to care between inpatient and outpatient settings.

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Chawla et al. (2016) studied this question.

synapsesocial.com/papers/69d6d05bfca0359822aa8ab8 https://doi.org/10.1093/trstmh/trw030

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Results from early programmatic implementation of Xpert MTB/RIF testing in nine countriesDiagnostic Study · 2014 · 175 citations
2Xpert® MTB/RIF for national tuberculosis programmes in low-income countries: when, where and how?Original Research · 2011 · 126 citations
3Understanding the barriers to setting up a healthcare quality improvement process in resource-limited settings: a situational analysis at the Medical Department of Kamuzu Central Hospital in Lilongwe, MalawiQualitative Study · 2014 · 344 citations
4In-hospital mortality rates and HIV: a medical ward review, Lilongwe, MalawiCohort Study · 2011 · 28 citations
5Time to Treatment and Patient Outcomes among TB Suspects Screened by a Single Point-of-Care Xpert MTB/RIF at a Primary Care Clinic in Johannesburg, South AfricaOriginal Research · 2013 · 85 citations

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