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April 1, 1993Journal of Applied Crystallography24,804 citations

PROCHECK: a program to check the stereochemical quality of protein structures

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RLRoman A. LaskowskiMMMalcolm W. MacArthurDMD. S. Moss

Key Points

  • The aim is to evaluate the stereochemical quality of protein structures using PROCHECK programs.
  • Utilized PROCHECK suite for detailed stereochemical checks of protein structures.
  • Provided residue-by-residue listings and plots for quality assessment.
  • Compared structures against well-refined models of similar resolution.
  • Identified regions requiring further investigation in protein structures.
  • Delivered comprehensive quality assessments for both solved and modeled protein structures.
  • Facilitated the analysis of existing protein structures for refinement.

Abstract

The PROCHECK suite of programs provides a detailed check on the stereochemistry of a protein structure. Its outputs comprise a number of plots in PostScript format and a comprehensive residue-by-residue listing. These give an assessment of the overall quality of the structure as compared with well refined structures of the same resolution and also highlight regions that may need further investigation. The PROCHECK programs are useful for assessing the quality not only of protein structures in the process of being solved but also of existing structures and of those being modelled on known structures.

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Cite This Study

Laskowski et al. (1993) studied this question.

synapsesocial.com/papers/69d6d1ed8dca315383ed933ahttps://doi.org/10.1107/s0021889892009944
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