Why the study?
Is slow coronary flow associated with decreased FFR and diffuse atherosclerosis on IVUS?
Is slow coronary flow associated with decreased FFR and diffuse atherosclerosis on IVUS?
Slow coronary flow is associated with decreased FFR and diffuse atherosclerosis on IVUS, suggesting it reflects epicardial resistance rather than isolated microvascular dysfunction.
SCF may reflect epicardial rather than isolated microvascular disease; leaves open whether FFR or IVUS alters management or outcomes.
We have demonstrated the decreased FFR in the patients with SCF. Decreased FFR levels have been attributed to increased resistance in the epicardial coronary arteries due to diffuse atherosclerotic disease which has been demonstrated by IVUS.
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Pekdemir et al. (2004) studied this question.